Delayed processing on MacOS shell

[RASdoto]

I'm currently running perf-ssr on a Mac. My project is using a Python script to first download sequences via the NCBI API and running Perf-ssr on the sequences on the Mac shell.

The shell execution is getting slower and slower everyday.

As a note I can say, the working folder is cleared of any residual files with an independant Python script. It's sometimes the shell is executed and the shell is stuck with only the command.

I'm looking for answers to optimize this issue with my script and (hopefully) improve my shell runtime.

P.s. I'm working with 1Mil sequences and have only gotten through to 500K. It's gradually slowed down and now it's only clearing 5 sequenceces in 15 minutes. Which is very slow considering I can download upto 400 seqeunces/min from NCBI API. Any troubleshooting advice from the developers would significantly speed up my project.