Irregular dosing

[ahmedsuleiman]

Hi Andrew,

Is it possible to introduce irregular dosing when creating the PopED database? E.g. switching from a loading dose to a maintenance dose, or having some irregular dosing intervals within the same group/arm.

Thanks a lot in advance.

Ahmed Suleiman

[Anks2030]

Hi Ahmed,
I also had the same question with @andrewhooker posted under below link
#56 (comment)

In an another case study the dosing was from same route sc, but I needed different loading and different maintenance dose so I used following code under # define initial conditions

dose_times = c(seq(from=0,to=336, by=84),seq(from=336,to=8568,by=TAU))