Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

how to read graph_test output of monocle 3 #716

Open
synatkeamsk opened this issue Apr 25, 2024 · 1 comment
Open

how to read graph_test output of monocle 3 #716

synatkeamsk opened this issue Apr 25, 2024 · 1 comment

Comments

@synatkeamsk
Copy link

Dear All,

I am using monocle 3 to perform Trajectory analysis and use deg <- graph_test(cds, neighbor_graph = "principal_graph") to examine genes that changed as a function of pseudotime. I am a bit unfamiliar with the output and have read the monocle3 documentation, but still unclear.

The output I got contain various columns such as gene names, status, p_value, morans_test_statistics, morans_I and q_value. I am wondering how do I know which genes are downregulated or upregulated based on these columns? I have attached the image of the output I got. Hope someone can help. Thanks in advance!

Best,

Capture

@synatkeamsk
Copy link
Author

Dear developers, @ctrapnell @kou @dcalderon @Loyale !

Hope you are well. I am wondering whether anyone of you could help answer my questions above. Recently, I have also try TradeSeq to find DEG from monocle3 object. What do you think about tradeseq. Hope you could spare a couple of minutes help because I am still stuck with it.

Kind Regards,

Synat

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant