Event modulation Index and Modulation significance level #82
Replies: 3 comments 7 replies
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Hi Jesus Take a look at the CellExplorer/calc_CellMetrics/calc_PSTH.m Line 101 in 69c4a1e
The modulation significance level is a KS-test also calculated in the same script:
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Hi Jesus I revisited this and made some modifications and improvements. The modulation index is now scaled between -1 and 1 as in your second reference, defined as the difference between the stimulation interval and the pre-stimulation interval, divided by their sum). I added a second measure called the stimulation ratio defined as the stimulation interval divided by the pre-stimulation interval. These are calculated from the averages of the intervals. I updated the documentation to reflect this: https://cellexplorer.org/datastructure/standard-cell-metrics/#event-metrics I also updated the preferences file of the Processing Module to allow you to define custom parameters for the PSTH: https://github.com/petersenpeter/CellExplorer/blob/master/preferences_ProcessCellMetrics.m
In your case, you could set the duration to 0.025 and the binDistribution to [0.34,0.33,0.33] this will give you a pre-stimulation baseline of 17ms and a stimulation interval of 16.5ms. I am working on a better method that allows you to set specific intervals. I will let you know when it is ready. |
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Hi peter when i get the Psth, using the script calc_Psth, i am trying to understand how the responsive curve is calculated, i see very high values. so i guess is in Hz? Thanks in advance |
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Hi Peter.
I am trying to get some information from PSTHs and rasters using Cell Explorer and i have seen that Cell Explorer gives you the "modulation Index". How is this parameter calculated?
I have seen in several papers that the values goes from -1 to 1, however Cell Explorer gives me values up to 200.
I would like also to know how Cell Explorer calculates the "Modulation Significance level", I could not find this information in the Website.
Thank you very much in advance
Jesus
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