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@FowlerLab

Fowler Lab

Laboratory of Douglas M. Fowler in the Department of Genome Sciences at the University of Washington.

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  1. Enrich2 Enrich2 Public

    Tool for deep mutational scanning experiments.

    Python 45 12

  2. Envision2017 Envision2017 Public

    We present Envision, an accurate predictor of protein variant molecular effect, trained using large-scale experimental mutagenesis data. All data and software in this study are freely available. Th…

    Jupyter Notebook 16 1

  3. Enrich2-Example Enrich2-Example Public

    Example deep mutational scanning dataset for Enrich2

    5

  4. VAMPseq VAMPseq Public

    We developed Variant Abundance by Massively Parallel Sequencing (VAMP-seq), which simultaneously measures the effects of thousands of missense variants on protein intracellular abundance, and appli…

    HTML 5 3

  5. simdms simdms Public

    Deep mutational scanning dataset simulator.

    Python 3

  6. 2017_GRAY_InformativeAA 2017_GRAY_InformativeAA Public

    To draw general conclusions about the effects of different amino acid substitutions, we analyzed 34,373 mutations in fourteen proteins whose effects were measured using large-scale mutagenesis appr…

    1 1

Repositories

Showing 10 of 18 repositories
  • cyp2c19_2c9 Public

    Analysis pipeline for "Understanding the CYP family tree through deep mutational scanning: A joint analysis of CYP2C19 and 2C9 variant abundance"

    FowlerLab/cyp2c19_2c9’s past year of commit activity
    0 1 0 0 Updated Sep 3, 2024
  • FowlerLab/VEP-calibrations’s past year of commit activity
    Python 0 0 0 0 Updated Jun 7, 2024
  • FowlerLab/2024_CSR_TFO’s past year of commit activity
    Python 0 0 0 0 Updated May 23, 2024
  • 2024_multistep Public

    Data and analysis for Popp, NA, et al., 2024.

    FowlerLab/2024_multistep’s past year of commit activity
    Promela 0 0 0 0 Updated May 2, 2024
  • FowlerLab/2022_SrcHsp90’s past year of commit activity
    Jupyter Notebook 0 0 0 0 Updated Nov 22, 2022
  • simdms Public

    Deep mutational scanning dataset simulator.

    FowlerLab/simdms’s past year of commit activity
    Python 3 GPL-3.0 0 0 0 Updated Sep 23, 2021
  • Enrich2 Public

    Tool for deep mutational scanning experiments.

    FowlerLab/Enrich2’s past year of commit activity
    Python 45 BSD-3-Clause 12 21 0 Updated Sep 22, 2021
  • 2020_dOTS Public

    Sequencing and statistical analysis for Rose, J.C., Popp, N.A., et al. 2020. Suppression of unwanted CRISPR/Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs. Nat. Comm.

    FowlerLab/2020_dOTS’s past year of commit activity
    Python 0 0 0 1 Updated Mar 25, 2021
  • 2020_CAVA Public

    Data and analyses associated with CAVA

    FowlerLab/2020_CAVA’s past year of commit activity
    0 0 0 0 Updated Oct 27, 2020
  • VKOR Public

    Analysis pipeline for manuscript "Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact."

    FowlerLab/VKOR’s past year of commit activity
    HTML 1 BSD-3-Clause 1 0 0 Updated Aug 31, 2020

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