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Analysis of lipid profiles on 16 children with different obesity conditions

In this repository I've included all the scripts produced to perform an analysis on lipidomics profiles of 16 children with different obesity conditions. At first, I had to reorder names and change the ontology, from LipidBlast ontology to LIPIDMAPS one. Then I've performed a multivariate analysis on this set of data, using a PCA method. Following the PCA, I decided to implement also lipidr package, that deal specifically with untargeted lipidomics data, in order to correctly parsing and analyze lipids and finally performing and enrichment analysis using both LSEA (a modified LSEA version, included in the package) and LION/web.

In a second script, called LOEnA.R, I've included all the lines of code produced to generate a dot plot in GSEA-like style.

Also, I've added my Quarto document (and corresponding pdf) where I've described what these data contains and give a brief analysis with PCA

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Lipidomics Analysis in a multi-group study

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