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dragstr model in Mutect2 WDL (#8716)
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davidbenjamin committed Mar 18, 2024
1 parent 8ee86e7 commit 141529b
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4 changes: 4 additions & 0 deletions scripts/mutect2_wdl/mutect2.wdl
Original file line number Diff line number Diff line change
Expand Up @@ -95,6 +95,7 @@ workflow Mutect2 {
# additional modes and outputs
File? realignment_index_bundle
String? realignment_extra_args
File? dragstr_model
Boolean run_orientation_bias_mixture_model_filter = false
Boolean make_bamout = false
Boolean compress_vcfs = false
Expand Down Expand Up @@ -178,6 +179,7 @@ workflow Mutect2 {
getpileupsummaries_extra_args = getpileupsummaries_extra_args,
variants_for_contamination = variants_for_contamination,
variants_for_contamination_idx = variants_for_contamination_idx,
dragstr_model = dragstr_model,
make_bamout = make_bamout,
run_ob_filter = run_orientation_bias_mixture_model_filter,
compress_vcfs = compress_vcfs,
Expand Down Expand Up @@ -380,6 +382,7 @@ task M2 {
File? gga_vcf_idx
File? variants_for_contamination
File? variants_for_contamination_idx
File? dragstr_model

File? gatk_override

Expand Down Expand Up @@ -459,6 +462,7 @@ task M2 {
~{"-pon " + pon} \
~{"-L " + intervals} \
~{"--alleles " + gga_vcf} \
~{"--dragstr-params-path " + dragstr_model} \
-O "~{output_vcf}" \
~{true='--bam-output bamout.bam' false='' make_bamout} \
~{true='--f1r2-tar-gz f1r2.tar.gz' false='' run_ob_filter} \
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