snoFlake: snoRNA-RBP Functional Interaction Network Models

A pipeline to gather snoRNA and RBP interactions to perform a sno-RBP interaction network analysis.

Author: Kristina Sungeun Song

Running the Snakemake workflow

For a dry-run of this Snakemake workflow, simply run the following code from CRSSANT/.

snakemake -n

To run this Snakemake workflow, simply run the following code from CRSSANT/.

snakemake --profile profile_slurm

OR

snakemake --profile profile_local

Types of snoRNA-RBP Interactions: ADD FIGURE

Step 0: Download and prepare environment

snoFlake is supported on Linux (tested on Ubuntu).

Installing Snakemake

Please follow the instructions to install the Snakemake workflow management tool. We recommend using Conda/Mamba to install Snakemake.

This Snakemake workflow has been tested with v7.32.4.

Step 1: Get input datasets from various sources

Step 2: Compute snoRNA and RBP interactions

Step 3: Build snoFlake on Cytoscape