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BioThings BioPlanet Pathway Gene

tursynay edited this page Dec 15, 2023 · 2 revisions

Homepage Link: https://tripod.nih.gov/bioplanet/

Description: The NCATS BioPlanet is a comprehensive, publicly accessible informatics resource that catalogues all pathways, their healthy and disease state annotations, and targets within and relationships among them. The BioPlanet integrates pathway annotations from publicly available, manually curated sources that have been subjected to thorough redundancy and consistency cross-evaluation via extensive manual curation. The browser supports interactive browsing, retrieval, and analysis of pathways, exploration of pathway connections, and pathway search by gene targets, category, and availability of bioactivity assays. We intend for such a platform to enable the rational construction of probing assays that could be used to query all of pathway space experimentally. The current version of the BioPlanet (v1.0) incorporates 1,658 distinct human pathways encompassing 9,818 human genes. In future releases, pathways for other species will be added as well as links to data from small molecule, gene expression and siRNA screens performed at NCATS and data from other researchers.

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