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Target Central Resource Database

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karafecho edited this page Dec 12, 2023 · 4 revisions

Homepage URL: http://juniper.health.unm.edu/tcrd/

Description: Target Central Resource Database (TCRD) is the central resource behind the Illuminating the Druggable Genome Knowledge Management Center (IDG-KMC). TCRD contains information about human drug targets, with special emphasis on four families of targets that are central to the NIH IDG initiative: GPCRs, kinases and ion channels (note that olfactory GPCRs are treated as a separate family). A key aim of the KMC is to classify the development/druggability level of targets.

Tclin - targets of approved drugs with known mechanism of action

Tchem - targets with drug or small molecule activity, but not a known mechanism of action

Tbio - targets without drug or small molecule activity, but suggested evidence of activity

Tdark - targets about which virtually nothing is known

Example record (summary of available data): image

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Knowledge Providers (KP)

Autonomous Relay Agents (ARA)

Autonomous Relay System (ARS)

Standards and Reference Implementation (SRI)

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