CPDB

Homepage Link: http://cpdb.molgen.mpg.de/CPDB

Description: ConsensusPathDB (CPDB) integrates interaction networks in Homo sapiens (human), Saccharomyces cerevisiae (yeast), and Mus musculus (mouse). This includes binary and complex protein-protein, genetic, metabolic, signaling, gene regulatory and drug-target interactions, as well as biochemical pathways, from multiple public resources for interactions and the CPDB team's curation of the literature. The interaction data are integrated in a complementary manner (avoiding redundancies), resulting in a seamless interaction network containing different types of interactions.

Example records: RHEB NCBIGene:6009 participates in the following pathways:

• mtor signaling pathway BIOCARTA:mtorpathway
• Phospholipase D signaling pathway - Homo sapiens (human) KEGG.PATHWAY:hsa00120
• PIP3 activates AKT signaling REACT:R-HSA-1257604
• Target Of Rapamycin (TOR) Signaling WIKIPATHWAYS:WP1471

Additional links:

• https://doi.org/10.1093/nar/gkab1128