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KinAce
Sierra Moxon edited this page Mar 8, 2024
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Homepage URL: https://kinace.kinametrix.com/#section-about
Description:
The KinAce web portal aggregates and visualizes the network of interactions between protein-kinases and their substrates in the human genome. To begin, click on one of the tabs above. Each tab provides a unique way to select a set of proteins and display the known kinase-substrate interactions between them. Data types include: proteins, pathways, domains, and custom protein sets.
KinAce uses data from:
- interactions from PhosphoSitePlus, iPTMnet and EPSD,
- kinase group information from KinHub, Coral and the Dark Kinase Knowledgebase,
- protein names from UniProt,
- gene symbols from HGNC,
- sets of proteins from select pathways in KEGG,
- sets of proteins having select domains from InterPro.
Example records:
![Screen Shot 2024-03-08 at 3 27 32 PM](https://private-user-images.githubusercontent.com/4561292/311391337-fbf82e91-11e2-4049-92c0-23671146e280.png?jwt=eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpc3MiOiJnaXRodWIuY29tIiwiYXVkIjoicmF3LmdpdGh1YnVzZXJjb250ZW50LmNvbSIsImtleSI6ImtleTUiLCJleHAiOjE3MjU5OTU5OTUsIm5iZiI6MTcyNTk5NTY5NSwicGF0aCI6Ii80NTYxMjkyLzMxMTM5MTMzNy1mYmY4MmU5MS0xMWUyLTQwNDktOTJjMC0yMzY3MTE0NmUyODAucG5nP1gtQW16LUFsZ29yaXRobT1BV1M0LUhNQUMtU0hBMjU2JlgtQW16LUNyZWRlbnRpYWw9QUtJQVZDT0RZTFNBNTNQUUs0WkElMkYyMDI0MDkxMCUyRnVzLWVhc3QtMSUyRnMzJTJGYXdzNF9yZXF1ZXN0JlgtQW16LURhdGU9MjAyNDA5MTBUMTkxNDU1WiZYLUFtei1FeHBpcmVzPTMwMCZYLUFtei1TaWduYXR1cmU9YWU2ZDMzNzg1ODBkMTA5OGEyNjA1NDVhY2FjOTgzMGUyYjRmYWU2ZGJkYzNjYTkwNGY5ZTU0YTk0ODYwMDgzNiZYLUFtei1TaWduZWRIZWFkZXJzPWhvc3QmYWN0b3JfaWQ9MCZrZXlfaWQ9MCZyZXBvX2lkPTAifQ.lJIyW2JgRujjQhmfBRwwlAOEPFwnXMTVvpnHYf1RnT8)